What is Rejuran

Rejuran is a remarkable skincare treatment that stands apart from other options on the market. Its key ingredient, Polynucleotides (PN), is highly effective at repairing and combating visible signs of aging. Derived from salmon sperm DNA, PN undergoes a purification process to remove immunogenic proteins and is then broken down into tiny fragments, creating a gel-based formulation that is both safe and highly compatible with human skin.

What makes Rejuran unique is its ability to harness bioactive DNA molecules to enhance skin elasticity, support the repair of damaged tissue, and stimulate natural regeneration. This advanced approach distinguishes it from conventional collagen-boosting treatments.

How does Rejuran work

Rejuran contains polynucleotide (PN), a powerful ingredient derived from salmon DNA. It is commonly used as an injectable treatment but can also be applied topically in combination with lasers or microneedling.

This formulation works on the layers of skin below the surface. Once introduced, Rejuran stimulates collagen production and boosts moisture levels, helping to improve elasticity, refine texture, and reduce the appearance of fine lines and wrinkles.

With proper guidance from a dermatologist, Rejuran offers several notable benefits, including reduced inflammation and irritation, enhanced hydration, improved overall texture, increased firmness and suppleness, skin regeneration and repair, and diminished stubborn wrinkles and fine lines.

How much does Rejuran cost

In Australia, Rejuran will usually cost between $500AUD-$1000AUD per ml, how much you need will depend on the area being treated (whole face, eyes or neck for example.) At the time of writing this, Rejuran has not been FDA approved in the USA though some people are able to access Rejuran products online. It is popularly used in South Korea where it was developed, other parts of Asia and Australia.

Different types of Rejuran

There are several types of Rejuran available on the market at the moment with unique properties and in so lending themselves to different specific uses.

Rejuran Healer: True to its name, this formulation is designed for skin repair and rejuvenation. With medium-viscosity PN, it works to refresh the face and body, combat early signs of aging, and improve skin texture. Ideal for individuals with sagging skin, wrinkles, and enlarged pores.

Rejuran HB: A perfect choice for those with dry skin, this version combines PN and Hyaluronic Acid (HA) to deeply hydrate and promote skin regeneration, enhancing moisture retention and overall skin health.

Rejuran I: For those struggling with dark circles, crow’s feet, and fine lines under the eyes, this specialized formula is tailored for the delicate eye area. It boosts elasticity and smooths imperfections, delivering results without the need for surgery.

Rejuran S: If acne scars, blemishes, dark spots, or surgical scars are a concern, this high-viscosity formula is designed for targeted scar treatment and skin tissue repair. It effectively fills in depressed scars and smooths out uneven skin textures, promoting a more refined and restored complexion.

How is a Rejuran treatment performed

A typical Rejuran treatment session is relatively quick, lasting between 30 and 45 minutes, depending on the specific concerns and areas being treated.

Before undergoing any cosmetic procedure, it is essential to consult with a board-certified dermatologist to ensure that Rejuran is the right choice for your skin needs. Your provider will assess your skin condition and advise on the best approach for achieving optimal results. It is also important to avoid certain medications and skincare products that may trigger irritation or inflammation before treatment. If you have yet to find a trusted dermatologist, consider visiting a reputable clinic that specializes in advanced skin treatments.

What are the risks and possible side effects of a Rejuran treatment

While Rejuran is considered safe, some individuals may experience minor side effects, which are generally related to the injection process rather than the product itself. Redness, swelling, and bruising at the injection site are common but typically resolve within a few days. Some people may also notice increased sensitivity in the treated area, though this discomfort usually fades quickly. Mild pain during and shortly after the procedure is possible, but it tends to be brief and manageable.

In rare cases, more serious complications can occur. Although allergic reactions are uncommon due to the biocompatibility of polynucleotides, they can still happen. There is also a small risk of infection, as with any injectable treatment, particularly if the procedure is not performed under sterile conditions.

Rejuran may not be suitable for everyone, as certain conditions serve as contraindications. Pregnant or breastfeeding individuals are advised against undergoing treatment due to a lack of research on its safety in these groups. Patients with active skin infections or inflammation near the injection site should postpone the procedure until their skin has fully healed. Additionally, those with a history of severe allergies or anaphylaxis should consult with their doctor beforehand to assess potential risks. Taking necessary precautions and working with an experienced provider can help ensure a safe and effective treatment experience.

How long does Rejuran last

Rejuran treatment results generally last between six and twelve months, with longevity influenced by factors like skin type, age, and lifestyle. While the first signs of improvement become visible within a few weeks of the initial session, achieving the best and most enduring effects typically requires a series of two to four treatments, scheduled three to four weeks apart. To maintain these benefits and preserve a refreshed, youthful appearance, follow-up sessions may be recommended once or twice a year.

How soon do you see results after a Rejuran treatment

The effects of Rejuran treatment begin to emerge within two to four weeks after the first session, with noticeable enhancements in skin texture, hydration, and elasticity. However, the most significant transformation typically becomes evident around four to six weeks, as the skin’s natural repair mechanisms and collagen production fully activate. To maximize results, a series of treatments is advised, allowing gradual improvements to unfold progressively with each session.

How many Rejan treatments do you need

For optimal results, an initial series of two to three treatments is recommended, spaced two to four weeks apart. Since skin continues to age, maintenance sessions may be necessary, with some individuals opting for treatments every six months, while others may find that once a year is sufficient.

Choosing a skilled and experienced provider is essential, as precise application into the intradermal layer of the skin ensures the most visible and long-lasting improvements. Proper technique plays a key role in achieving the best possible outcome.